What is RRM?
What is RRM?
RRM (Restorative Reproductive Medicine) is a medical discipline that looks to identify and treat the root cause of reproductive problems, aiming to treat, optimize and restore the patient's health
"What's wrong?"
"What's wrong?"
RRM focusses on this question, then restores or optimizes natural function without suppressing or bypassing the problem
Cycle or Fertility Charting
Cycle or Fertility Charting
Fertility or cycle charts are an important tool to carefully time tests and medications in women; changes in the chart empower her to know her body and the effects of treatments
Restorative Andrology
Restorative Andrology
An emerging field in RRM that looks exclusively at identifying and restoring male reproductive function
RRM is not one charting method
RRM is not one charting method
All believe in empowering the patient with scientifically sound and well researched knowledge about their fertility
IIRRM offers unparalleled education
Education
The International Institute for Restorative Reproductive Medicine offers unparalleled opportunities for continuing education and professional development
Together.
Together.
Transforming Reproductive Medicine.
September 24-27 2025
September 24-27 2025
Join us in Zagreb or Online for the 2025 International Clinical & Scientific Congress for Restorative Reproductive Medicine!

Together. Transforming Reproductive Medicine.

The International Institute for Restorative Reproductive Medicine is the leading voice in uniting providers and researchers who share a common belief that patients deserve scientifically-based and well researched reproductive health care services that cooperate with and restore reproductive function. To address reproductive health problems, restorative reproductive medicine (RRM) exclusively focuses investigations and treatments on identifying and correcting abnormalities, restoring or optimizing normal reproductive function.

Membership

Becoming a member of the International Institute for RRM allows you to join a growing network of professionals and supporters who are helping transform reproductive medicine. As a member, you take an active role in shaping a future in which restorative reproductive medicine, backed by quality research and years of experience, becomes the standard of care in reproductive health services.
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Research

One of the cornerstones of our organization, IIRRM sponsors and endorses research that focuses on a restorative approach to reproductive health. Our goal is simple…..every patient, every clinician, every teacher should have access to well studied, scientifically sound clinical knowledge of restorative reproductive medicine, including research.
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Online Education

Explore live and recorded webinars, research training, and resources and an interactive forum with case discussions. Listen and learn without the formality of an online learning system including regular Research Updates, monthly Journal Clubs and Grand Rounds.
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Upcoming Events & Webinars

Upcoming continuing medical education and case discussions for IIRRM members. To view all upcoming webinars and register click here.
 

New Programs & News

RRM Clinician Recognition

The RRM Clinician Recognition Program aims to acknowledge clinicians who demonstrate a commitment to delivering exceptional care in restorative reproductive medicine (RRM), support high standards in RRM care, and maintain a current pool of clinicians who are actively providing care for both patient referrals and for FABM/NFP teachers to access.  Apply for this program today.
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New Research suggesting DHEA treatment during pregnancy can reduce the risk of miscarriage for women with low oestrogen levels

New research has been published on DHEA treatment during pregnancy and risk of miscarriage for women with low oestrogen levels. This study is the first of its kind to show DHEA supplementation effectively increased estradiol levels and reduced miscarriage rates in pregnancies with low serum estradiol. Low estradiol levels could serve as a measurable biomarker for targeted RRM therapy in recurrent miscarriage.
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Hope After IVF : Restorative Reproductive Medicine

For women with infertility who fail to become pregnant with IVF, there is now new hope.  A research paper published in Frontiers in Medicine studied the outcomes of 403 couples who were treated with Restorative Reproductive Medicine (RRM) after failing to become pregnant with IVF, some having undergone as many as 9 unsuccessful rounds of IVF.
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Access Past Webinars

Missed a webinar? Webinars are recorded for viewing when convenient for you and available for free in the member portal. CME credit is also available when noted in the activity.

Research Updates: Surgical Management of Endometriosis

Dr. Patrick Yeung presents updates on surgical management of Endometriosis and results of their new paper, a prospective cohort study aimed to evaluate the effectiveness of optimal excision surgery for endometriosis in reducing repeat surgery rates compared to historical data from ablation procedures, with the cohort of patients showing a notably low repeat surgery rate of 2.5% (15 out of 620 patients) following optimal excision, contrasting with suggested historical rates of 40-60% for ablation (Bozdağ 2015). The team also looked at the relationship between hormonal suppression use before surgery and the stage of endometriosis, finding no significant correlation, suggesting that hormonal suppression may not prevent disease progression.
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Sperm DNA Integrity and Male Health 

This activity provides an update on sperm DNA Integrity/Damage and testing, the relationship between male fertility and health and between sperm DNA damage and health of the offspring and discusses what we can do to improve male health and fertility. Presented by Preben Christensen, PhD, who has been researching sperm quality and reduced fertility since 1996, which in 2006 led to the founding of SPZ Lab - which offers an examination of sperm cell DNA integrity (SDI-testing).
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RRM Journal Club

Journal Club is your chance to stay up to date in the latest RRM research and application to clinical practice. These sessions provide a critical appraisal of published research relevant to the field of restorative reproductive medicine. IIRRM runs separate monthly Journal Clubs Meetings in English, Spanish, Ukrainian. Recent recordings and articles are listed for members to review below.

Journal Club (Ukrainian): Maternal periconception hyperglycemia, preconception diabetes, and risk of major congenital malformations in offspring

Article: Ran S Rotem, Marc G Weisskopf, Brian Bateman, Krista Huybrechts, Sonia Hernández-Diáz, Maternal periconception hyperglycemia, preconception diabetes, and risk of major congenital malformations in offspring, Human Reproduction, Volume 39, Issue 12, December 2024, Pages 2816–2829, https://doi.org/10.1093/humrep/deae233
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Journal Club (in Spanish): 2024 Evidence-based guideline: premature ovarian insufficiency

ESHRE, ASRM, CREWHIRL and IMS Guideline Group on POI, Panay, N., Anderson, R. A., Bennie, A., Cedars, M., Davies, M., Ee, C., Gravholt, C. H., Kalantaridou, S., Kallen, A., Kim, K. Q., Misrahi, M., Mousa, A., Nappi, R. E., Rocca, W. A., Ruan, X., Teede, H., Vermeulen, N., Vogt, E., & Vincent, A. J. (2024). Evidence-based guideline: premature ovarian insufficiency†‡. Climacteric : the journal of the International Menopause Society, 27(6), 510–520. https://doi.org/10.1080/13697137.2024.2423213
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Journal Club (in English): The Effect of Berberine on Reproduction and Metabolism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Control Trials

Xie L, Zhang D, Ma H, et al. The Effect of Berberine on Reproduction and Metabolism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Control Trials. Evid Based Complement Alternat Med. 2019;2019:7918631. Published 2019 Dec 13. doi:10.1155/2019/7918631
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IIRRM Journal Club (Español): Relationship between chronic endometritis and fallopian tube obstruction and its influence on pregnancy outcome after fallopian tubal recanalization

Artículo: Sun, Yu et al. “Relationship between chronic endometritis and fallopian tube obstruction and its influence on pregnancy outcome after fallopian tubal recanalization.” Therapeutic advances in reproductive health vol. 18 26334941241308413. 25 Dec. 2024, doi:10.1177/26334941241308413
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