May Journal Club: Menstrual Preconditioning for the Prevention of Major Obstetrical Syndromes in Polycystic Ovarian Syndrome
Presented by Dr. Eddie Fleming. The presence of multiple ovarian cysts, anovulation, and endometrial progesterone resistance in the neonate seems remarkably similar to ovarian and endometrial features of the polycystic ovary syndrome (PCOS) of adolescent and adult women. Could cyclic administration of clomiphene citrate for a period to be determined by vascular response be an appropriate tool to reduce the risk of major obstetric syndromes by menstrual preconditioning?
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