Dr. Ezenkwele received her medical degree from the University of Nigeria, Nsukka. She did her fellowship in Obstetrics and Gynecology at the West African Postgraduate College of Medicine/University of Nigeria Teaching Hospital, Enugu.  Since then she has worked at a variety of clinics and hospitals.

Dr. Ezenkwele is a certified Fertilitycare Practitioner, Natural Family Planning Medical Consultant and received her Diploma in Tropical Medicine and Hygiene at the London School of Hygiene and Tropical Medicine.  She currently works at the University of Nigeria Teaching Hospital as a Senior Lecturer, NaPro Technologist, Fertilitycare Practitioner and Honorary Consultant OBGYN since 2012. She is also the Takemi Fellow at the Harvard T.H Chan School of Public Health in the Department of Global Health and Population.