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Grand Rounds: BCL6 testing and the relationship of other endometrial biomarkers in detection of endometriosis

28 April 2022 8:00 PM - 9:00 PM

Presented by Bruce A Lessey MD, PhD.

Dr. Lessey presents on the relationship of the ReceptivaDx test (BCL6 test) and other endometrial markers for the detection of inflammation of the uterine lining commonly associated with endometriosis.  Consider previewing a recent journal club presented by Joe Stanford "Unexplained recurrent pregnancy loss and unexplained infertility: twins in disguise" published Fox et al.1 for additional background on BCL6 and endometriosis.

This webinar is approved for 1.00 Online Only, Live AAFP Prescribed Credit*.

Register here. A link to join the webinar will be emailed after registering.



Bruce A Lessey MD, PhD is a physician-scientist with a long-standing interest in basic and translational research on endometrial function. He received a PhD with a focus on steroid receptor biology, later expanding into human research under the direction of Kathryn Horowitz at the University of CO School of Medicine on breast cancer, and later on the endometrium at Duke University 1984-8 with Dr. Kenneth McCarty Jr.


After becoming a Professor in the Department of OBGYN at the University of North Carolina Chapel Hill (UNC-Chapel Hill) Professor Lessey continued NIH-funded research on endometriosis including important DNA microarray studies in collaboration with UCSF. In 2003 I relocated to Greenville SC to become Division Director at the Greenville Health System (now Prisma Health).

In 2019 , Professor Lessey moved to Wake Forest where the current focus of his laboratory continues to be on the role of endometrial receptivity and endometrial dysfunction in endometriosis, infertility and pregnancy loss. Collaborations between his lab and Dr Anthony Atala in the Center for Regenerative Medicine will focus on novel methods for endometrial regeneration in a non-human primate model.  These studies show great promise for the treatment of uterine defects including Asherman’s syndrome in women desiring future pregnancy.


Continuing Medical Education Credits and Activity Information :

Reference [image]: Yoo, JY., Kim, T.H., Fazleabas, A.T. et al. KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance. Sci Rep 7, 6765 (2017). https://doi.org/10.1038/s41598-017-04577-w

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April 28
8:00 PM - 9:00 PM BST
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