This webinar explores the concept that endometriosis and PCOS represent opposite outcomes of variation in HPG axis development, with endometriosis linked to low prenatal and postnatal testosterone, while PCOS is associated with high prenatal testosterone. Endometriosis and PCOS could be considered as reflecting maladaptive extremes of female fitness-related adaptations, which has direct implications for therapy and fertility restoration in women with endometriosis or PCOS.

Involved in a number of research areas, Prof. Crespi also studies the evolutionary biology of risks for endometriosis and PCOS, from fetal programming to life histories.

Credit Statement: The AAFP has reviewed Investigating Endometriosis and PCOS as Diametric Conditions and deemed it acceptable for up to 1.5 Enduring Materials, Self-Study AAFP Prescribed credit. Term of Approval is from 1/12/2023 to 1/12/2024. Physicians should claim only the credit commensurate with the extent of their participation in the activity.