January 2022 JC

January Journal Club: Unexplained recurrent pregnancy loss and unexplained infertility

“Is B-cell CLL/lymphoma 6 (BCL6) endometrial expression, a surrogate biomarker of endometriosis, elevated in women with unexplained recurrent pregnancy loss (uRPL) and unexplained infertility (UI) compared to fertile subjects?”. What could this study suggest for potential treatment and future investigations for recurrent miscarriage and unexplained pregnancy loss? Review the findings of this study in the IIRRM Journal club with Dr. Joe Stanford.

Journal Club: Reproductive life in women with celiac disease

Review the findings with Dr Joseph Stanford, of a population-based cohort study examining the impact of celiac disease on women’s reproductive health from Grode et. al.1 in October’s Journal club. “How does celiac disease (CD) influence women’s reproductive life, both prior to and after the diagnosis?” – Download the article before viewing the webinar.

August Grand Rounds: The role of diet and lifestyle on reproductive health

Prof Sunni Mumford will discuss emerging research investigating the role of vitamin D and other lifestyle and dietary factors on female reproductive health and couple fertility. Dr. Mumford is a reproductive and nutritional epidemiologist and Earl Stadtman Investigator in the Epidemiology Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Her research focuses on modifiable dietary and lifestyle factors across the life course th…

June Grand Rounds: Updates on FABMS effectiveness for Avoiding Pregnancy

Dr. Urrutia reviews the methodology and main findings of 2018 review on FABM effectiveness for avoiding pregnancy and disucsses the important limitations of the data including population-based differences in effectiveness, especially among breastfeeding and postpartum individuals. She also introduces and identifies clinical decision-making tools providers and patients regarding choosing an FABM to avoid pregnancy, reviews new technologies currently being applied to FABM use, and discusses the role of the FDA in clearing fertility awareness apps for contraception.

May Journal Club: Dopamine, vascular permeability, and inflammation as relates to endometrium, pelvic pain, and pregnancy loss

Dr. Carpentier shares his experience with and looks into the science behind the use of dexamphetamine treatment as a novel off-label treatment for a number of female chronic disorders that do not respond well to conventional therapy including recurrent pregnancy loss, inflammation, and ongoing pain.    The primary article of focus for this journal club, “The neurotransmitter dopamine modulates vascular permeability in the endothelium”, along with a list of references can be downloaded to accompany the webinar.