The Institute for Restorative Reproductive Medicine
Together. Transforming Reproductive Medicine.
Dr. Patrick Yeung reviews the differences between ART/IVF and Restorative Reproductive Medicine (RRM) and the importance to offer alternatives to IVF to patients. Current surgical approaches and factors to consider in timing a laparoscopy for suspected endometriosis.
Dr. José Antonio and Dr. Stanford facilitate Q & A following the presentation.
Bruce A Lessey MD, PhD. discusses the biomarkers of endometrial receptivity and diagnostics for endometriosis, including the use of BCL6 testing. Review timing and synchrony of the embryo, progesterone, and endometrium that occur in a successful pregnancy. Discuss how to approach treatment and predict pregnancy outcomes with this information.
Professor Stephan Gordts presents a systematic minimal invasive exploration of so-called “unexplained infertility” (normal ultrasound/normal HSG) reveals the presence of pelvic pathology on 50-70 % of patients. In the absence of other fertility impairing factors, like male infertility, he looks at the different treatments of these pathologies to create the possibilities for normal conception.
Dr. Paul Carpentier provides an update and review on the use of Lisinopril for Male infertility, discussing the article, “Angiotensin-converting enzymes play a dominant role infertility”. The biochemistry background of angiotensin-converting enzymes (ACEs) in Male Fertility is also reviewed, with discussion following.
How should we apply and use semen analysis testing and results in RRM and when should a semen analysis be considered for couples trying to conceive? What parameters should be evaluated, how are they measured and what is the clinical significance of the results?
Are there laboratory tests that have been abandoned because of ART, that could have application towards RRM? What about at-home “male fertility” testing kits? View this presentation and discussion with Craig Turczynski, PhD.
“Is B-cell CLL/lymphoma 6 (BCL6) endometrial expression, a surrogate biomarker of endometriosis, elevated in women with unexplained recurrent pregnancy loss (uRPL) and unexplained infertility (UI) compared to fertile subjects?”. What could this study suggest for potential treatment and future investigations for recurrent miscarriage and unexplained pregnancy loss? Review the findings of this study in the IIRRM Journal club with Dr. Joe Stanford.
In our last Journal club of 2021 Dr Stanford facilitates and reviews the article, Early pregnancy ultrasound measurements and prediction of first-trimester pregnancy loss: A logistic model. The authors suggest a statistical model for determining the likelihood of first-trimester pregnancy loss based on ultrasound markers in early pregnancy.
Review the findings with Dr Joseph Stanford, of a population-based cohort study examining the impact of celiac disease on women’s reproductive health from Grode et. al.1 in October’s Journal club. “How does celiac disease (CD) influence women’s reproductive life, both prior to and after the diagnosis?” – Download the article before viewing the webinar.
Dr. Keenan discuss vaccine safety in pregnancy, looking article reporting preliminary data on the safety of messenger RNA (mRNA) Covid-19 vaccines in pregnancy taken from the v-safe surveillance system and pregnancy registry. Oppotunrity to comment and share articles in the RRM Forum.
